List of References

We have compiled a list of the references to medical sources used in our website.

Should you wish to pursue this information further, these are very good articles to read in detail.

  1. Bright, R. (2010). Adipose Derived Stromal Cells to Treat Joint Disease. Journal of Cosmetic Surgery & Medicine, Volume 5(Issue 3).
  2. Bright, B., Bright, R., Bright, P. and Limaye, A. (2018). Ankylosing spondylitis, chronic fatigue and depression improved after stromal vascular fraction treatment for osteoarthritis: a case report. Journal of Medical Case Reports, 12(1).
  3. Pak, J., Lee, J., Park, K., Park, M., Kang, L. and Lee, S. (2017). Current use of autologous adipose tissue-derived stromal vascular fraction cells for orthopedic applications. Journal of Biomedical Science, 24(1).
  4. Le Blanc, K. (2006) ‘Mesenchymal stromal cells: Tissue repair and immune modulation’, Cytotherapy, 8(6), pp. 559–561. doi: 10.1080/14653240601045399.
  5. Human Adipose-Derived stem cells suppress Elastase-Induced Murine abdominal Aortic inflammation and Aneurysm expansion through Paracrine factors (2016) Cell Transplantation, . doi: 10.3727/096368916×692212.
  6. Cuervo, B., Rubio, M., Sopena, J., Dominguez, J., Vilar, J., Morales, M., Cugat, R. and Carrillo, J. (2014) ‘Hip osteoarthritis in dogs: A Randomized study using Mesenchymal stem cells from Adipose tissue and plasma rich in growth factors’, International Journal of Molecular Sciences, 15(8), pp. 13437–13460. doi: 10.3390/ijms150813437.
  7. Jo, C.H., Lee, Y.G., Shin, W.H., Kim, H., Chai, J.W., Jeong, E.C., Kim, J.E., Shim, H., Shin, J.S., Shin, I.S., Ra, J.C., Oh, S. and Yoon, K.S. (2014) ‘Intra-Articular injection of Mesenchymal stem cells for the treatment of osteoarthritis of the knee: A proof-of-concept clinical trial’, STEM CELLS, 32(5), pp. 1254–1266. doi: 10.1002/stem.1634.
  8. Wu, L., Cai, X., Zhang, S., Karperien, M. and Lin, Y. (2013) ‘Regeneration of articular cartilage by adipose tissue derived mesenchymal stem cells: Perspectives from stem cell biology and molecular medicine’, Journal of Cellular Physiology, 228(5), pp. 938–944. doi: 10.1002/jcp.24255.
  9. Gibbs, N., Diamond, R., Sekyere, E. and Thomas, W. (2015) ‘Management of knee osteoarthritis by combined stromal vascular fraction cell therapy, platelet-rich plasma, and musculoskeletal exercises: A case series’, Journal of Pain Research, , p. 799. doi: 10.2147/jpr.s92090.
  10. MONTEIRODECASTRO, G. (2004) ‘Th1 and th2 cytokine immunomodulation by gangliosides in experimental autoimmune encephalomyelitis’, Cytokine, 26(4), pp. 155–163. doi: 10.1016/j.cyto.2004.02.009.
  11. Diekman, B.O. and Guilak, F. (2013) ‘Stem cell-based therapies for osteoarthritis’, Current Opinion in Rheumatology, 25(1), pp. 119–126. doi: 10.1097/bor.0b013e32835aa28d.
  12. Michalek, J. (2015) ‘Autologous adipose tissue-derived stromal vascular fraction cells application in patients with osteoarthritis’, Cell Transplantation, . doi: 10.3727/096368915×686760.
  13. Pak, J., Lee, J.H. and Lee, S.H. (2013) ‘A novel biological approach to treat Chondromalacia Patellae’, PLoS ONE, 8(5), p. e64569. doi: 10.1371/journal.pone.0064569.
  14. Freitag, J., Bates, D., Boyd, R., Shah, K., Barnard, A., Huguenin, L. and Tenen, A. (2016) ‘Mesenchymal stem cell therapy in the treatment of osteoarthritis: Reparative pathways, safety and efficacy – a review’, BMC Musculoskeletal Disorders, 17(1). doi: 10.1186/s12891-016-1085-9.
  15. Barry, F. and Murphy, M. (2013) ‘Mesenchymal stem cells in joint disease and repair’, Nature Reviews Rheumatology, 9(10), pp. 584–594. doi: 10.1038/nrrheum.2013.109.
  16. Yanai, T. (2005) ‘Repair of large full-thickness articular cartilage defects in the rabbit: THE EFFECTS OF JOINT DISTRACTION AND AUTOLOGOUS BONE-MARROW-DERIVED MESENCHYMAL CELL TRANSPLANTATION’, Journal of Bone and Joint Surgery – British Volume, 87-B(5), pp. 721–729. doi: 10.1302/0301-620x.87b5.15542..
  17. Paz Rodriguez, J., Murphy, M.P., Hong, S., Madrigal, M., March, K.L., Minev, B., Harman, R.J., Chen, C.-S., Timmons, R.B., Marleau, A.M. and Riordan, N.H. (2012) ‘Autologous stromal vascular fraction therapy for rheumatoid arthritis: Rationale and clinical safety’, International Archives of Medicine, 5(1), p. 5. doi: 10.1186/1755-7682-5-5.
  18. The basics of osteoarthritis (2016) Available at: http://www.webmd.com/osteoarthritis/guide/osteoarthritis-basics#1 (Accessed: 20 October 2016).
  19. 2016, S. of V. (2014) Osteoarthritis. Available at: https://www.betterhealth.vic.gov.au/health/conditionsandtreatments/osteoarthritis (Accessed: 20 October 2016)
  20. Mayfieldclinic, (2017). Spine Anatomy, Anatomy of the Human Spine. [online] Mayfieldclinic.com. Available at: http://www.mayfieldclinic.com/pe-anatspine.htm [Accessed 9 Mar. 2017].
  21. Spine Health. (2017). Defintion: Bulging vs Herniated Spinal Disc – Alternative Treatments. [online] Available at: http://www.spine-health.com/forum/discussion/7734/treatment/alternative-treatments/defintion-bulging-vs-herniated-spinal-disc [Accessed 9 Mar. 2017].
  22. Modric, J. (2017). Herniated (Extruding, Slipped) Disc; Cervical, Lumbar Radiculopathy | eHealthStar. [online] Ehealthstar.com. Available at: http://www.ehealthstar.com/conditions/bulging-herniated-disc [Accessed 9 Mar. 2017].
  23. info. (2017). Neuropathic Pain. [online] Available at: http://patient.info/health/neuropathic-pain [Accessed 9 Mar. 2017].
  24. Estebe, J. and Atchabahian, A. (2017). The nerve. European Journal of Anaesthesiology, p.1.
  25. Lundborg, G., Gelberman, R., Minteer-Convery, M., Lee, Y. and Hargens, A. (1982). Median nerve compression in the carpal tunnel—Functional response to experimentally induced controlled pressure. The Journal of Hand Surgery, 7(3), pp.252-259.
  26. Vickers, R., Karsten, E., Lilischkis, R. and Flood, J. (2014). A preliminary report on stem cell therapy for neuropathic pain in humans. Journal of Pain Research, p.255.
  27. Sacerdote, P., Niada, S., Franchi, S., Arrigoni, E., Rossi, A., Yenagi, V., de Girolamo, L., Panerai, A. and Brini, A. (2013). Systemic Administration of Human Adipose-Derived Stem Cells Reverts Nociceptive Hypersensitivity in an Experimental Model of Neuropathy. Stem Cells and Development, 22(8), pp.1252-1263.
  28. Juhl, A., Karlsson, P. and Damsgaard, T. (2016). Fat grafting for alleviating persistent pain after breast cancer treatment: A randomized controlled trial. Journal of Plastic, Reconstructive & Aesthetic Surgery, 69(9), pp.1192-1202.
  29. (2017). Muscle Strains. [online] Available at: http://www.healthline.com/health/strains [Accessed 8 Mar. 2017].
  30. com. (2017). [online] Available at: https://www.epainassist.com/images/ [Accessed 8 Mar. 2017].
  31. (2017). The Basics of Muscle Strains. [online] Available at: http://www.webmd.com/fitness-exercise/guide/muscle-strain [Accessed 8 Mar. 2017].
  32. Kaariainen, M., Jarvinen, T., Jarvinen, M., Rantanen, J. and Kalimo, H. (2000). Relation between myofibers and connective tissue during muscle injury repair. Scandinavian Journal of Medicine and Science in Sports, 10(6), pp.332-337.
  33. Physioworks (2017). Ligament Injury. [online] Available at: http://physioworks.com.au/Injuries-Conditions/Regions/ligament-injury [Accessed 8 Mar. 2017].
  34. Petersen, W. and Tillmann, B. (1999). Structure and vascularization of the cruciate ligaments of the human knee joint. Anatomy and Embryology, 200(3), pp.325-334.
  35. Kamimura, T. and Kimura, M. (2014). Meniscal Repair of Degenerative Horizontal Cleavage Tears Using Fibrin Clots: Clinical and Arthroscopic Outcomes in 10 Cases. Orthopaedic Journal of Sports Medicine, 2(11).
  36. Solomon, E., Berg, L., Evans, R., King, D., Martin, D., McGill, J., Milne, J. and Panen, M. (2005). Biology. 1st ed. Belmont, CA: Thomson-Brooks/Cole.
  37. Anon, (2017). [online] Available at: https://www.local-physio.co.uk/sc/content/articles/ [Accessed 9 Mar. 2017].
  38. Condé-Green, A., Marano, A., Lee, E., Reisler, T., Price, L., Milner, S. and Granick, M. (2016). Fat Grafting and Adipose-Derived Regenerative Cells in Burn Wound Healing and Scarring. Plastic and Reconstructive Surgery, 137(1), pp.302-312.
  39. Pitts, J., Al-Sayegh, H., Freeman, M. and Centeno, C. (2015). Anterior cruciate ligament tears treated with percutaneous injection of autologous bone marrow nucleated cells: a case series. Journal of Pain Research, p.437.
  40. DOI: 10.18410/jebmh/2015/964 J of Evidence Based Med & Hlthcare, pISSN- 2349-2562, eISSN- 2349-2570/ Vol. 2/Issue 41/Oct. 12, 2015 Page 7088
  41. Hernigou, P, et al, Percutaneous Autologous Bone-Marrow Grafting for Nonunions: Surgical Technique, Journal of Bone and Joint Surgery, 2006; 88;322-327
  42. Hernigou, P, et al, Percutaneous Autologous Bone-Marrow Grafting for Nonuions: Influence of the Number and Concentration of Progenitor Cells, Journal of Bone and Joint Surgery, 2005; 87-A;1430-1437 Surgery, 2005; 87-A; 1430-1437; eJBJS, July 2005;
  43. Lieberman JR, Commentary & Perspective on “Percutaneous Autologous Bone Marrow Grafting for Nonunions” by Hernigou Pet al, Journal of Bone and Joint
  44. Connolly, JF, et al, Development of an Osteogenic Bone-Marrow Preparation, Journal of Bone and Joint Surgery, June 1989; 684-691
  45. Schuman L; J Bone Joint Surg (Br) 2002;84-B:364-8 Arthroscopic treatment for osteochondral defects of the talus: Results at follow-up at 2 to 11 years
  46. Tornero-Esteban, P., Hoyas, J., Villafuertes, E., Rodríguez-Bobada, C., López-Gordillo, Y., Rojo, F., Guinea, G., Paleczny, A., Lópiz-Morales, Y., Rodriguez-Rodriguez, L., Marco, F. and Fernández-Gutiérrez, B. (2015). Efficacy of supraspinatus tendon repair using mesenchymal stem cells along with a collagen I scaffold. Journal of Orthopaedic Surgery and Research, 10.
  47. Manning, C., Martel, C., Sakiyama-Elbert, S., Silva, M., Shah, S., Gelberman, R. and Thomopoulos, S. (2015). Adipose-derived mesenchymal stromal cells modulate tendon fibroblast responses to macrophage-induced inflammation in vitro. Stem Cell Research & Therapy, 6(1).
  48. Lee SY, Kim W, Lim C, Chung SG. Treatment of lateral epicondylosis by using allogeneic adipose-derived mesenchymal stem cells: a pilot study. Stem Cells. 2015;33(10):2995–3005
  49. de Girolamo L, Grassi M, Viganò M, Orfei CP, Montrasio UA, Usuelli F. Treatment of achilles tendinopathy with autologous adipose-derived stromal vascular fraction: results of a randomized prospective clinical trial. The Orthopaedic Journal of Sports Medicine. 2016;4(7):supplement 4.
  50. Englund M, Guermazi A, Gale D, Hunter DJ, Aliabadi P, Clancy M, Felson DT. Incidental meniscal findings on knee MRI in middle-aged and elderly persons. N Engl J Med. 2008;359(11):1108–15.
  51. DeHaven KE. Decision-making factors in the treatment of meniscus lesions. Clin Orthop Relat Res. 1990;252:49–54.
  52. Newman AP, Daniels AU, Burks RT. Principles and decision making in meniscal surgery. Arthroscopy. 1993;9(1):33–51.
  53. Petty CA, Lubowitz JH. Does arthroscopic partial meniscectomy result in knee osteoarthritis? A systematic review with a minimum of 8 years’ follow-up. Arthroscopy. 2011;27(3):419–24.
  54. Finnilä, M., Thevenot, J., Aho, O., Tiitu, V., Rautiainen, J., Kauppinen, S., Nieminen, M., Pritzker, K., Valkealahti, M., Lehenkari, P. and Saarakkala, S. (2016). Association between subchondral bone structure and osteoarthritis histopathological grade. Journal of Orthopaedic Research, 35(4), pp.785-792.
  55. Netzer, C., Urech, K., Hügle, T., Benz, R., Geurts, J. and Schären, S. (2016). Characterization of subchondral bone histopathology of facet joint osteoarthritis in lumbar spinal stenosis. Journal of Orthopaedic Research, 34(8), pp.1475-1480.
  56. Hayes, C., Jamadar, D., Welch, G., Jannausch, M., Lachance, L., Capul, D. and Sowers, M. (2005). Osteoarthritis of the Knee: Comparison of MR Imaging Findings with Radiographic Severity Measurements and Pain in Middle-aged Women. Radiology, 237(3), pp.998-1007.
  57. Cassar-Pullicino, V., Darby, A. and Davies, M. (2004). Subchondral insufficiency fractures of the femoral head. European Radiology, 14(2), pp.201-207.
  58. Van Ochten, J., Mos, M., van Putte-Katier, N., Oei, E., Bindels, P., Bierma-Zeinstra, S. and van Middelkoop, M. (2014). Structural abnormalities and persistent complaints after an ankle sprain are not associated: an observational case control study in primary care. British Journal of General Practice, 64(626), pp.e545-e553.
  59. Li, G., Yin, J., Gao, J., Cheng, T., Pavlos, N., Zhang, C. and Zheng, M. (2013). Subchondral bone in osteoarthritis: insight into risk factors and microstructural changes. Arthritis Research & Therapy, 15(6), p.223.
  60. Lauvrud, A., Kelk, P., Wiberg, M. and Kingham, P. (2016). Characterization of human adipose tissue-derived stem cells with enhanced angiogenic and adipogenic properties. Journal of Tissue Engineering and Regenerative Medicine, p.n/a-n/a.
  61. Nguyen, A., Guo, J., Banyard, D., Fadavi, D., Toranto, J., Wirth, G., Paydar, K., Evans, G. and Widgerow, A. (2016). Stromal vascular fraction: A regenerative reality? Part 1: Current concepts and review of the literature. Journal of Plastic, Reconstructive & Aesthetic Surgery, 69(2), pp.170-179.
  62. Chen, X., Yan, L., Guo, Z., Chen, Z., Chen, Y., Li, M., Huang, C., Zhang, X. and Chen, L. (2016). Adipose-derived mesenchymal stem cells promote the survival of fat grafts via crosstalk between the Nrf2 and TLR4 pathways. Cell Death and Disease, 7(9), p.e2369.
  63. Zachar, L., Bačenková, D. and Rosocha, J. (2016). Activation, homing, and role of the mesenchymal stem cells in the inflammatory environment. Journal of Inflammation Research, Volume 9, pp.231-240.
  64. Fu, Y., Karbaat, L., Wu, L., Leijten, J., Both, S. and Karperien, M. (2017). Trophic effects of mesenchymal stem cells in tissue regeneration. Tissue Engineering Part B: Reviews.
  65. Rohban, R. and Pieber, T. (2017). Mesenchymal Stem and Progenitor Cells in Regeneration: Tissue Specificity and Regenerative Potential. Stem Cells International, 2017, pp.1-16.
  66. Matsumoto, T., Cooper, G., Gharaibeh, B., Meszaros, L., Li, G., Usas, A., Fu, F. and Huard, J. (2009). Cartilage repair in a rat model of osteoarthritis through intraarticular transplantation of muscle-derived stem cells expressing bone morphogenetic protein 4 and soluble flt-1. Arthritis & Rheumatism, 60(5), pp.1390-1405.
  67. Chang, Y., Liu, H., Wu, K. and Ding, D. (2016). Mesenchymal Stem Cells and Their Clinical Applications in Osteoarthritis. Cell Transplantation, 25(5), pp.937-950.
  68. Riordan, N., Ichim, T., Min, W., Wang, H., Solano, F., Lara, F., Alfaro, M., Rodriguez, J., Harman, R., Patel, A., Murphy, M., Lee, R. and Minev, B. (2009). Non-expanded adipose stromal vascular fraction cell therapy for multiple sclerosis. Journal of Translational Medicine, 7(1), p.29.
  69. Rohani, L., Johnson, A., Arnold, A. and Stolzing, A. (2013). The aging signature: a hallmark of induced pluripotent stem cells?. Aging Cell, 13(1), pp.2-7.
  70. Sugihara, S., Yamamoto, Y., Matsuura, T., Narazaki, G., Yamasaki, A., Igawa, G., Matsubara, K., Miake, J., Igawa, O., Shigemasa, C. and Hisatome, I. (2007). Age-related BM-MNC dysfunction hampers neovascularization. Mechanisms of Ageing and Development, 128(9), pp.511-516
  71. Koh, Y., Choi, Y., Kwon, S., Kim, Y. and Yeo, J. (2013). Clinical results and second-look arthroscopic findings after treatment with adipose-derived stem cells for knee osteoarthritis. Knee Surgery, Sports Traumatology, Arthroscopy, 23(5), pp.1308-1316.
  72. Kokai, L., Traktuev, D., Zhang, L., Merfeld-Clauss, S., DiBernardo, G., Lu, H., Marra, K., Donnenberg, A., Donnenberg, V., Meyer, E., Fodor, P., March, K. and Rubin, J. (2016). Adipose Stem Cell Function Maintained with Age: An Intra-Subject Study of Long-Term Cryopreserved Cells. Aesthetic Surgery Journal, p.sjw197.
  73. Hendrich, C., Engelmaier, F., Waertel, G., Krebs, R. and Jäger, M. (2009). Safety of autologous bone marrow aspiration concentrate transplantation: initial experiences in 101 patients. Orthopedic Reviews, 1(1), p.32.
  74. Peter F. Ullrich, O. (2017). What Is Degenerative Disc Disease?. [online] Spine-health. Available at: https://www.spine-health.com/conditions/degenerative-disc-disease/what-degenerative-disc-disease [Accessed 14 Jul. 2017].
  75. Schroeder, J. (2015). Stem cells for spine surgery. World Journal of Stem Cells, 7(1), p.186.
  76. Jo, C., Lee, Y., Shin, W., Kim, H., Chai, J., Jeong, E., Kim, J., Shim, H., Shin, J., Shin, I., Ra, J., Oh, S. and Yoon, K. (2014). Intra-Articular Injection of Mesenchymal Stem Cells for the Treatment of Osteoarthritis of the Knee: A Proof-of-Concept Clinical Trial. STEM CELLS, 32(5), pp.1254-1266.
  77. Marsh, J., Birmingham, T., Giffin, J., Isaranuwatchai, W., Hoch, J., Feagan, B., Litchfield, R., Willits, K. and Fowler, P. (2016). Cost-effectiveness analysis of arthroscopic surgery compared with non-operative management for osteoarthritis of the knee. BMJ Open, 6(1), p.e009949.
  78. Zhang, L., Wang, P., Zhou, Z., He, H., Yan, D., Zu, Y. and Wang, W. (2017). Use of immune modulation by human adipose-derived mesenchymal stem cells to treat experimental arthritis in mice. American Journal of Translational Research, (2595–2607).
  79. González, M., Gonzalez-Rey, E., Rico, L., Büscher, D. and Delgado, M. (2009). Treatment of experimental arthritis by inducing immune tolerance with human adipose-derived mesenchymal stem cells. Arthritis & Rheumatism, 60(4), pp.1006-1019.
  80. Weyand, C. and Goronzy, J. (2017). Immunometabolism in early and late stages of rheumatoid arthritis. Nature Reviews Rheumatology, 13(5), pp.291-301.
  81. Ansboro, S., Roelofs, A. and De Bari, C. (2017). Mesenchymal stem cells for the management of rheumatoid arthritis. Current Opinion in Rheumatology, 29(2), pp.201-207.
  82. Lopez-Santalla, M., Menta, R., Mancheño-Corvo, P., Lopez-Belmonte, J., DelaRosa, O., Bueren, J., Dalemans, W., Lombardo, E. and Garin, M. (2016). Adipose-derived mesenchymal stromal cells modulate experimental autoimmune arthritis by inducing an early regulatory innate cell signature. Immunity, Inflammation and Disease, 4(2), pp.213-224.
  83. Forouzanfar, F., Amin, B., Ghorbani, A., Ghazavi, H., Ghasemi, F., Sadri, K., Mehri, S., Sadeghnia, H. and Hosseinzadeh, H. (2017). New approach for the treatment of neuropathic pain: Fibroblast growth factor 1 gene-transfected adipose-derived mesenchymal stem cells. European Journal of Pain.
  84. Moosmayer, S., Gärtner, A. and Tariq, R. (2017). The natural course of nonoperatively treated rotator cuff tears: an 8.8-year follow-up of tear anatomy and clinical outcome in 49 patients. Journal of Shoulder and Elbow Surgery, 26(4), pp.627-634.
  85. Wu, F., Nerlich, M. and Docheva, D. (2017). Tendon injuries. EFORT Open Reviews, 2(7), pp.332-342.
  86. Michalek, J., Vrablikova, A., Darinskas, A., Lukac, L., Prucha, J., Skopalik, J., Travnik, J., Cibulka, M. and Dudasova, Z. (2018). Stromal vascular fraction cell therapy for osteoarthritis in elderly: Multicenter case-control study. Journal of Clinical Orthopaedics and Trauma.
  87. Pak, J., Lee, J., Pak, N., Park, K., Jeon, J., Jeong, B. and Lee, S. (2018). Clinical Protocol of Producing Adipose Tissue-Derived Stromal Vascular Fraction for Potential Cartilage Regeneration. Journal of Visualized Experiments, (139).
  88. Iturriaga, L., Hernáez-Moya, R., Erezuma, I., Dolatshahi-Piouz, A. and Orive, G. (2018). Advances in stem cell therapy for cartilage regeneration in osteoarthritis. Expert Opinion on Biological Therapy.
  89. Zwolanek, D., Satué, M., Proell, V., Godoy, J., Odörfer, K., Flicker, M., Hoffmann, S., Rülicke, T. and Erben, R. (2017). Tracking mesenchymal stem cell contributions to regeneration in an immunocompetent cartilage regeneration model. JCI Insight, 2(20).
  90. Bateman, M., Strong, A., Gimble, J. and Bunnell, B. (2018). Using Fat to Fight Disease: A Systematic Review of Non-Homologous Adipose-Derived Stromal/Stem Cell Therapies. STEM CELLS.
  91. Thirumala, S., Gimble, J. and Devireddy, R. (2010). Cryopreservation of stromal vascular fraction of adipose tissue in a serum-free freezing medium. Journal of Tissue Engineering and Regenerative Medicine, 4(3), pp.224-232.
  92. Barwinska, D., Traktuev, D., Merfeld-Clauss, S., Cook, T., Lu, H., Petrache, I. and March, K. (2018). Cigarette Smoking Impairs Adipose Stromal Cell Vasculogenic Activity and Abrogates Potency to Ameliorate Ischemia. STEM CELLS, 36(6), pp.856-867.

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