Psoriasis & Biological Treatments – A Case Report

May 31,2018

Macquarie Stem Cells has provided this information to educate the public based on peer reviewed, published scientific and medical documents. We don’t aim to encourage consumers to seek out such treatments prior to an assessment by a health professional to determine your suitability for treatment. This is obtained directly from NCBI Pubmed Literature. There were no financial sponsors identified for this study. We aim to provide you with an unbiased range of treatments that are available aside from biological therapy, this is discussed in ‘other-options’  page on our website. We do not directly treat psoriasis.

TITLE: First-in-man I.V. injection of stromal vascular fraction in psoriasis: a case study.” (Comella et al., 2018)

Published: 21st March 2018
Journal of Medical Case Reports


“Stromal vascular fraction (SVF) is a mixture of adipose-derived stem cells/mesenchymal stem cells, endothelial/progenitors, pericytes, fibroblasts, and other cells obtained from fat tissue. A small sample of fat or adipose tissue can be obtained under local anesthesia using a cannula. After an enzymatic digestion and centrifugation, the adipocytes (fat cells) are removed to obtain an SVF. Here, we describe the rationale and, to our knowledge, the first clinical implementation of SVF intravenously in a patient with severe psoriasis.”  (Comella et al., 2018)


“Adipose tissue (60 mL) was collected under local anesthesia via a mini-lipoaspirate procedure. The SVF was separated from the adipocytes via centrifugation after an enzymatic digestion. The cells were resuspended in normal saline and injected via bolus push intravenous. The subject was monitored over a period of 12 months for safety (adverse events), medication changes, and quality of life parameters.” (Comella et al., 2018)


“The patient did not report any safety concerns and did not experience any severe adverse events. The patient demonstrated a significant decrease in symptoms with a noticeable difference in skin quality appearance. Psoriasis area and severity index score went from 50.4 at baseline to 0.3 at 1 month follow-up”(Comella et al., 2018)


“Overall, the patient reported improved quality of life and willingness to continue treatments. This successful initial case study demonstrates that this may be a feasible treatment plan for patients suffering from psoriasis.” (Comella et al., 2018)

REF: Comella, K., Parlo, M., Daly, R. and Dominessy, K. (2018). First-in-man intravenous implantation of stromal vascular fraction in psoriasis: a case study. International Medical Case Reports Journal, Volume 11, pp.59-64.

TAGS: Macquarie Stem Cells, Dr. Ralph Bright, Psoriasis Research, Biological Therapy for Psoriasis, Biological treatment, Macquarie Stem Cells biology therapy


Remember, any surgical or invasive procedure carries risks. Before proceeding, you should seek a second opinion from an appropriately qualified health practitioner.

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