NEW OARSI Guidelines for patients suffering from Osteoarthritis

The new guidelines recommend a set of non-pharmacological core treatments as appropriate for all individuals, these are listed below.

  • Land & Water based exercises
  • Strength Training
  • Self Education
  • Weight Management – the OARSI guidelines make a specific recommendation of achieving a 5% weight loss within a 20-week period to be effective at treating knee OA. (1)


  • Topical NSAIDs (anti-inflammatory creams) are recommended as appropriate for all patients with knee-only OA and in a scientific review, were found overall to be safer and better tolerated compared to oral NSAIDs (anti-inflammatory tables). (1)
  • Due to increased safety concerns about toxicity, acetaminophen/paracetamol was given an “uncertain” recommendation for all patients with comorbidities. (1)
  • Oral and transdermal opioid painkillers were given an “uncertain” recommendation for all patient groups due to concerns about increased risks for adverse and serious adverse events. (1)
  • Glucosamine and chondroitin were both found to be “not appropriate” for all patients when used for disease modification and “uncertain” for all patients when used for symptom relief. (1)


  • Balneotherapy, defined as using baths containing thermal mineral waters, was evaluated for the first time and found to be an appropriate therapy for patients with multi-joint OA and comorbidities, as this group has few other treatment options. (1)
  • The prescription drug duloxetine was evaluated for the first time and found to be an appropriate treatment for knee-only OA patients without comorbidities and all multi-joint OA patients. (1)

Additionally to the OARSI Guidelines
Stem Cell Therapy is showing significant growth. Based on the current 2017 literature review by Dr. Pak,  “Stem Cells have a great clinical potential to treat various orthopedic disorders as seen in human studies. Adipose SVF may be worthwhile to try in individuals for whom medical treatment has failed and for whom surgical options are not available”.
(Pak J. et al, 2017.) (2)

1. REF: Osteoarthritis Research Society International. (2017). OARSI Guidelines. [online] Available at: [Accessed 22 Sep. 2017].

2. REF: Pak, J., Lee, J., Park, K., Park, M., Kang, L. and Lee, S. (2017). Current use of autologous adipose tissue-derived stromal vascular fraction cells for orthopedic applications. Journal of Biomedical Science, 24(1).


Tags: Macquarie Stem Cells, Dr. Bright, Osteoarthritis Treatment, Dr. Ralph Bright, Stem Cell Therapy, Stem Cell Treatment, Stem Cells for Arthritis

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