Published: 18th Jul 2018
Expert opinion of Biological Therapy Journal
Introduction: “Osteoarthritis (OA) is a progressive joint disease that compromises the structural integrity of cartilage tissue. Conventional treatments based on medication or surgery are nowadays inefficient and cell-based therapy has emerged as one of the most promising methods for cartilage regeneration. The first therapy developed for cartilage defects was Autologous Chondrocyte Implantation (ACI), but in the last few decades stem cells (SCs) from different sources have been proposed as a possible alternative for OA.”(Iturriaga et al., 2018)
Areas Covered: “Stem cells sources and available delivery procedures (scaffolds/hydrogels) are presented, along with the main issues arisen in this regard. Thereafter, pre-clinical and clinical trials performed in recent years are reviewed in order to take a glance towards the potential benefits that such therapies could deliver to the patients.”(Iturriaga et al., 2018)
Expert Opinion: “Stem cells have proven their potential and safety for Osteoarthritis treatment. Nevertheless, there are still many questions to be resolved before their widespread used in clinical practice, such as the treatment mechanism, the best cell source, the most appropriate processing method, the most effective dose and delivery procedure, and their efficacy. In this sense, long-term follow-up and larger randomized controlled trials utilizing standardized and established outcome scores are mandatory to make objective conclusions.”(Iturriaga et al., 2018)
REF: Iturriaga, L., Hernáez-Moya, R., Erezuma, I., Dolatshahi-Piouz, A. and Orive, G. (2018). Advances in stem cell therapy for cartilage regeneration in osteoarthritis. Expert Opinion on Biological Therapy.
TAGS: Macquarie Stem Cells, Possibilities of Biological Treatments, Focusing on Osteoarthritis, Macquarie Stem Cells treating osteoarthritis, Dr. Ralph Bright biological treatment, expert opinion journal
Remember, any surgical or invasive procedure carries risks. Before proceeding, you should seek a second opinion from an appropriately qualified health practitioner.